Extraction and Phytochemical Characterization of Aegle Marmelos Leaves and Their Evaluation for Antiulcer Activities of Albino Rats

In this study ethanolic extract of Aegle marmelos was evaluated for its anti-ulcer activity against aspirininduced gastric ulcer in albino rats. Various biochemical parameters such as gastric volume, pH of gastric content, free acidity and total acidity, total carbohydrate content such as total protein, hexoses, hexosamine, fucose and sialic acid were estimated in alcoholic precipitate of gastric juice were examined on the test and control group of animals. The extract concentration of 250 and 500 mg/kg exhibited a protective effect on ulcer-induced models in a dose dependent manner and was comparable with the standard drugs Lansprazole. The extract of Aegle marmelos showed significant reduction in gastric volume, free and total acidity and ulcer index. The extracts possess significant gastro protective activity as compared with standard drug. The present study revealed that the extract of Aegle marmelos leaves had ulcer protective activity comparable with standard drugs Lansprazole, which may be mediated by its antioxidant effects.